Mystic Defender is a two-dimensional action run and gun video game released for the Sega Genesis.

Mystic Defender takes place in an alternate Japan fantasy setting in which the anarchistic sorcerer Zareth kidnaps a young woman named Alexandra.

Not long after the kidnapping, Zareth's plan becomes apparent as Azuchi castle - the dwelling of Zao - rises from the waters.

Finally, the player can acquire a spherical power that launches ricocheting spheres around the screen which multiply when fully charged.

Aside from these powers, the player can also use a screen-clearing attack that summons a three-headed dragon which destroys all enemies and fired shots onscreen.