N-Methylethanolamine

With both an amine and a hydroxyl functional groups, it is a useful intermediate in the chemical synthesis of various products including polymers and pharmaceuticals.

In order to obtain high yields of the desired target product, the reactants are continuously fed to a flow reactor and reacted with a more than two-fold excess of methylamine.

N-Methylethanolamine is a clear, colorless, hygroscopic, amine-like smelling liquid which is miscible with water and ethanol in any ratio.

Being a base, N-methylaminoethanol forms neutral salts with fatty acids, which are used as surfactants (soaps) with good emulsifying properties and find applications in textile and personal care cleansing products.

Such amides also act as flow improvers and pour point depressants in heavy oils and middle distillates.

[7] N-methylaminoethanol plays a role as a building block for the synthesis of crop protection compounds and pharmaceuticals, such as in the first stage of the reaction sequence to the antihistamine and antidepressant mianserin (Tolvin) and to the non-analgesic Nefopam (Ajan).

Skeletal formula of N-methylethanolamine
Ball-and-stick model of the N-methylethanolamine molecule