Niels Peder Christian Holsøe (27 November 1826 – 1 January 1895) was a Danish architect, known for the numerous railway stations he designed across Denmark in his capacity of head architect of the Danish State Railways.

He was the son of pastor Lauritz Christian Holsøe (1789-1862) and Vilhelmine Euphrosyne Margrethe, née Feddersen (1797-1871).

He was initially trained as a mason, and later was a private student of Gustav Friedrich Hetsch (1788–1864).

[1] He designed a number of public buildings, especially railway stations in cities including Nyborg (1865), Silkeborg (1871), Varde (1874), Ringkøbing (1875), Ribe (1883), Svendborg (1876), Aarhus East (1877), Thisted (1881), Faaborg (1882), Assens (1883–84) and Helsingør (with Heinrich Wenck; 1889–91).

In addition, he designed the Hotel Marienlyst in Helsingør (1860–61), and Ugerløse Church (1875-76), and was responsible for the renovation of Aarhus Hospital (1878–89).