It connects the centre of Senegal to Basse Casamance in the south by a route which traverses the Gambia at the mouth of the River Gambia.

The road runs in a south-westerly direction from its junction with the N4 road at Kaolack via Sokone to the mouth of the River Gambia, where there is a ferry crossing to Banjul.

From Banjul the road runs south-eastwards via Diouloulou to reconnect with the N4 at Bignona.

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