[2] The constituency is composed of the South Karachi localities of Aram Bagh, Civil Line, Clifton, Defence, Gizri, Mithadar, Kharadar, Nanak Wara, part of Ranchore Line, Saddar, and Serai Quarter.

[6] Dr. Arif Alvi of PTI won the 2013 elections with a total of 76,305 votes.

[8] On 18 May, a day before the re-polling, PTI leader Zahra Shahid Hussain was assassinated outside her house.

Alvi of PTI was declared as a Member of the National Assembly of Pakistan from NA-250 Constituency of Karachi.

On 5 September 2018, Arif Alvi tendered his resignation[11] from the National Assembly as he was elected as the 13th President of Pakistan.