2JAV, 2W5A, 2W5B, 2WQO, 2XK3, 2XK4, 2XK6, 2XK7, 2XK8, 2XKC, 2XKD, 2XKE, 2XKF, 2XNM, 2XNN, 2XNO, 2XNP, 4A4X, 4AFE475118005ENSG00000117650ENSMUSG00000026622P51955O35942NM_001204182NM_001204183NM_002497NM_010892NP_001191111NP_001191112NP_002488NP_035022Serine/threonine-protein kinase Nek2 is an enzyme that in humans is encoded by the NEK2 gene.

[8][9] Protein kinase which is involved in the control of centrosome separation and bipolar spindle formation in mitotic cells and chromatin condensation in meiotic cells.

Regulates kinetochore microtubule attachment stability in mitosis via phosphorylation of NDC80.

Involved in regulation of mitotic checkpoint protein complex via phosphorylation of CDC20 and MAD2L1.

Plays an active role in chromatin condensation during the first meiotic division through phosphorylation of HMGA2.