Previous sponsors of the show include UPS, Applebee's, Call of Duty, Courtyard by Marriott, Subway and Panera.

The show was initially hosted by Mike Tirico along with analysts Joe Theismann, Craig James, Phil Simms and Ron Jaworski.

Former presenters include Mike Tirico, Bill Parcells, Michael Irvin, and Sterling Sharpe.

On occasion, the crew appeared on-site at the game, but for the most part the show was aired from the studios in Bristol, Connecticut.

In 2006, the show began appearing at the Monday Night Football site live as the game moved to ESPN from ABC.

Also, in 2006 Monday Night Countdown introduced a new logo and new graphics as part of The Syndicate's new NFL package for ESPN.

In the same fashion as all ESPN NFL studio shows, Monday Night Countdown adopted ABC's alternate football musical theme, though presented as a shuffle.

Beginning with the 2007 NFL season, the show cutback its onsite presence by having its main anchor team at ESPN studios in Bristol, but still kept a set at the actual game site.

The Bristol team was Berman, Jackson, Mortensen, Mike Ditka, Keyshawn Johnson, and Cris Carter.

Additionally, Monday Night Countdown debuted a new logo resembling its other NFL-themed studio-show properties, along with a new graphics package that is also used for MNF.

However, Berman and the Monday Night Countdown crew did the show on November 21 from Estadio Azteca in Mexico City for the game between the Oakland Raiders and Houston Texans, and December 12 from Gillette Stadium in Foxborough, Massachusetts.

She replaced Chris Berman, who departed after 30 seasons of hosting NFL-themed studio shows, though he still appeared in occasional segments.

Therefore, the lineup was Suzy Kolber, Adam Schefter, Randy Moss, Steve Young, and Louis Riddick.

After being at the network's New York City facilities due to the COVID-19 pandemic the previous year, Monday Night Countdown returned to the game site for the first time in two seasons.

Fellow newcomers Ryan Clark and Marcus Spears would also be joining the show, with Griffin and Schefter returning.

Van Pelt would also host the postgame show and anchor SportsCenter with SVP from the site of Monday Night Countdown.

ET); when ABC announced in September that it would simulcast an additional 10 games due to the 2023 Hollywood labor disputes, local affiliates kept the 7:30–8:00 p.m.

Jason Kelce (who retired the previous season) joined ESPN and later replaced Robert Griffin III, the latter of whom was fired in August, along with former Sunday NFL Countdown host Samantha Ponder.