Episodes were uploaded on Fridays at 10 p.m. Eastern Time (ET) on Peacock in the United States and the WWE Network internationally.

The show premiered on February 18, 2022, as a replacement for 205 Live, and it went head-to-head with rival promotion All Elite Wrestling's program, Rampage.

[1] On February 15, 2022, WWE announced that 205 Live would be replaced by a new show called NXT Level Up, which would stream in 205 Live's former Friday night slot at 10:00 p.m. Eastern Time (ET) on Peacock in the United States and the WWE Network internationally, airing directly after SmackDown.

The commentators for the show were Blake Howard and Byron Saxton, and the ring announcer was Sarah Schreiber.

On December 20, 2024, it was reported that NXT Level Up was being canceled and replaced by a new reality series, WWE LFG, which is set to premiere on February 16, 2025.