Na Chaluai (Thai: นาจะหลวย, pronounced [nāː tɕā.lǔaj]; Northeastern Thai: นาจะหลวย, pronounced [nâː tɕā.lǔaj]) is a district (amphoe) in the southern part of Ubon Ratchathani province, northeastern Thailand.

The Ministry of Interior created the "minor district" (king amphoe) Na Chaluai on 1 February 1972, when the three tambons (sub-districts) Na Chaluai, Phon Sawan, and Non Sombun were split off from Det Udom district.

This area was a battle field of Communist Party of Thailand and the Royal Thai Army during the time of Vietnam War.

[citation needed] Neighboring districts are (from the west clockwise) Nam Yuen, Det Udom, Buntharik and the Laotian province of Champasak.

The district is divided into six sub-districts (tambons), which are further subdivided into 68 villages (mubans).