Nadolol, sold under the brand name Corgard among others, is a medication used to treat high blood pressure, heart pain, atrial fibrillation, and some inherited arrhythmic syndromes.
[3] Common side effects include dizziness, feeling tired, a slow heart rate, and Raynaud syndrome.
[7] Nadolol is used to treat hypertension and for long-term treatment of angina pectoris and is approved by the FDA for these purposes.
[18] Nadolol and other beta blockers should be used with cautions in people with heart failure and its use should not be abruptly stopped.
Nadolol's inhibition of beta-1 receptors in the heart and kidney leads to its effects on lowering blood pressure.
[citation needed] Nadolol is classified as a beta blocker with low lipophilicity and hence lower potential for crossing the blood–brain barrier.