Nagao Tamekage (長尾 為景, c. 1486 or 1489 – December, 1536 or January 29, 1543) was a retainer of Japanese feudal lord Uesugi Fusayoshi, and a daimyō in his own right, during Japan's Sengoku period.

[1] Tamekage was born as the son of Nagao Yoshikage, the deputy military governor of Echigo.

According to George Bailey Sansom, Nagao Tamekage's career makes him representative of the emergence of the daimyōs, and the shift of regional power from the shugo (constables ), governors, and other government officials to independent lords.

It is believed that Tamekage "arranged" for correspondence between himself and the brothers to be discovered by an ally of Yoshimune, which would lead to their executions, perhaps a quicker route to weakening the Jinbo than the possibly ill-conceived plot with Nagakiyo.

Tamekage then engaged Uesugi Akisada, and defeated him as well, with the help of Hōjō Sōun, another growing power in the region.