It is the terminus of the Nishi Kyushu Shinkansen and the Nagasaki Main Line, as well as the westernmost high-speed Shinkansen railway station in Japan.

The station is connected by the Kamome Shinkansen service and the Relay Kamome limited express to Hakata, and by the Seaside Liner rapid service to Sasebo.

Nagasaki Electric Tramway services call at a stop in front of the station.

The conventional line station has two elevated island platforms serving five tracks.

[1] The Shinkansen station has two island platforms serving four tracks.