The hospital is situated south of Jomhuri, on Hafez Street.

Its original building belongs to early-Pahlavi architectural style.

On 4 August 2003 it was declared part of the Iranian Cultural Heritage and registered under number 9494.

The founder of the hospital endowment was Malektaj Firuz (Najm al-Saltaneh), the daughter of Qajar prince Nosrat-od-Dowleh Firouz Mirza.

Najmieh was the first modern private hospital in Tehran with a special fund earmarked for the care of poor patients.