Mohammad Namazi founded this hospital with 22 residential villas for physicians in 1950.

The admission capacity of the hospital rose from 200 to 750 beds.

[1] The first liver transplant was performed in 1993 in Shiraz University Hospital (Namazi).

The first living-related kidney transplantation performed at Shiraz University Hospital dates back to 1968.

The hospital has an active oncology department publishing papers regularly.