As an actress, Nana has starred in various television dramas such as Love Weaves Through a Millennium (2015), The Good Wife (2016), Kill It (2019), and Justice (2019).

[2] She graduated from Ochang High School [ko] in Cheongju[3] and was a participant in the 2009 Asia Pacific Super Model Contest.

[9] In December she joined fellow K-pop stars Hyolyn, Hyuna, Hyoseong, and Nicole to form the super group Dazzling Red for SBS Gayo Daejun, performing the song "This Person".

[21] In August 2014, Nana participated in the Chinese fashion elimination show Muse Dress,[22] and emerged runner-up in the competition.

[31] Following her success on the small screen, Nana was cast alongside her The Good Wife co-star, Yoo Ji-tae in the crime comedy film The Swindlers (Conman), as the only female lead.

[41] In April 2020 it was announced Nana would join Park Sung-hoon as the lead actress for KBS's upcoming drama Memorials.

[43] Nana also made her return to music after 6 years through the drama with the release of her first soundtrack, "Our Memories in Summer" (우리의 여름처럼) with co-star Park Sung-hoon.

[44] On September 7, it was confirmed that Nana would star in a new MBC drama Oh My Ladylord with Lee Min-ki set to premiere on March 24, 2021.

[45] After the completion of Oh My Ladylord, it was announced on May 28, 2021, that Nana was cast in Netflix's upcoming series Glitch as "Heo Bora" alongside actress Jeon Yeo-been.