Her message emphasized the need for low and middle-income countries to strengthen comprehensive and evidence-based cancer control policies and programs.

[8] On October 7, 2008, Brinker hosted a symposium on "Breast Cancer Global Awareness" at the Blair House where First Lady Laura Bush attended.

[9] As Chief of Protocol, Brinker expanded the role of the office through outreach programs intended to foster better relationships with the Diplomatic Corps.

[14] Hungarian President Ferenc Mádl awarded Brinker with the Order of Merit, Medium Class, Cross Adorned with Star, for her work in advancing bilateral relations and in recognition of her charity activities.

[15][16] The Promise Fund of Florida was created by Ambassador Nancy G. Brinker, Julie Fisher Cummings and Laurie Silvers in 2018.

[19] In 1992, Vice President Dan Quayle invited her to chair a subcommittee monitoring research, progress and development in the fight against breast cancer.

[19] Brinker was a bundler for George W. Bush when he was running for office, helping to organize and collect campaign contributions from other donors.

[21] And on December 24, 2008, President Bush appointed her to the board of trustees of the John F. Kennedy Center for the Performing Arts for a six-year term.