Although appearing in major films, Guild never achieved as much fame at 20th Century Fox, the studio that had signed her to a seven-year contract, as she had hoped, and eventually stopped acting.

[3] After her picture was published in a spread on campus fashions, Guild received screen tests at five Hollywood studios, and she was signed by 20th Century Fox.

She played a dual role as Marie Antoinette and the hypnotized love interest of Orson Welles in the 1949 adaptation of Alexandre Dumas’ historical novel about Count Cagliostro and the Affair of the Diamond Necklace.

After leaving Fox, she appeared in movies as a freelance and as a contract star at Universal-International, where she appeared in Little Egypt, Abbott and Costello Meet the Invisible Man picture and the Francis the Talking Mule movie Francis Covers the Big Town (1953).

[5] She appeared occasionally on television and briefly returned to the movies in Otto Preminger's Such Good Friends (1971).