In 1995, Lublin founded the organization Dress for Success, starting with $5,000 in seed money and a group of nuns in Harlem.

[6] From August 2003 to October 2015, Lublin oversaw the growth of Do Something and led the effort to begin awarding more grant money to younger candidates seeking social change.

Broadcast on VH1 (through 2013), they were the first televised awards show celebrating volunteerism, and featured hosts including Jane Lynch (2011), cast members of New Girl (2012),[7] and Sophia Bush (2013).

[12][13] In 2013, while still CEO of Do Something, Lublin developed her first TED talk into the foundation for a new nonprofit organization, Crisis Text Line.

[14] In 2020, after multiple complaints about management, Crisis Text Line staffers staged a virtual walkout and Twitter campaign demanding the Board of Directors create an "anti-racist" work environment.

[22] Lublin was named to the World Economic Forum's Young Global Leaders (2007), one of Glamour magazine's Women of Worth (2006), received Fast Company's Fast 50 Award (2002), and was named the NYC Women's Commission Woman of the Year (2000)[23] as well as the Schwab Foundation's Social Entrepreneur of the Year (2016).

[24] In 2017 she was featured as a protagonist in the podcast series by Reid Hoffman (Linkedin co-founder), Masters of Scale, among other businessmen of success such as Mark Zuckerberg, John Elkann and Brian Chesky.