The Nanke served in the imperial court, but many of Fujiwara no Tamenori's descendants later became samurai families such as Itō, Nikaidō, Sagara and Kudō.

Shortly after the beginning of Nara period, Muchimaro became the head of Ministry of Civil Services in 718.

Prince Nagaya was grandson of Emperor Tenmu, but not a son of Fujiwara family, he was therefore seen as a threat by Muchimaro and his three brothers.

After successfully removing Prince Nagaya in 729, Muchimaro rose to Dainagon, "Counselor of the first rank".

[4] Nanke further prospered in the Nara period as Nakamaro, the second son of Muchimaro, gained the trust of Empress Kōken and was given the name Emi no Oshikatsu.