Nanofountain probe

By controlling the geometry of the meniscus through hold time and deposition speed, various inks and biomolecules could be patterned on a surface, with sub 100 nm resolution.

[1] Integration of continuous liquid ink feeding within the NFP facilitates more rapid deposition and eliminates the need for repeated dipping, all while preserving the sub-100-nanometer resolution of DPN.

The platform is capable of constructing complex, highly-functional nanoscale devices from a diverse suite of materials (e.g., nanoparticles, catalysts (increase rate of reaction), biomolecules, and chemical solutions).

[3] Demonstrated nanopatterning capabilities include: • Biomolecules (proteins, DNA) for biodetection assays or cell adhesion studies • Functional nanoparticles for drug delivery studies and nanosystems making (fabrication) • Catalysts for carbon nanotube growth in nanodevice fabrication • Thiols for directed self-assembly of nanostructures.

Taking advantage of the unique tip geometry of the NFP nanomaterials are directly injected into live cells with minimal invasiveness.

Optical image of an array (left) and SEM image of the tip (right)
Microfabrication sequence
In vitro single cell injection using NFP