Fujioka made her professional debut on 15 September 2009, scoring a second-round technical knockout (TKO) victory against Napaporn Boonchuon (5–6, 3 KOs) at the Korakuen Hall in Tokyo, Japan.
[2] After winning her first three fights, all by TKO, she faced Kanittha Kokietgym (8–2, 2 KOs) for the vacant WBC-OPBF female minimumweight title on 24 September 2010, at the Korakuen Hall.
Fighting for the first time outside of Japan, Fujioka suffered the first defeat of her career in her attempt at a third world title via UD, with the judges' scorecards reading 96–94, 97–94 and 97–93.
[9] She bounced back from defeat with a split decision (SD) win against Mariana Juárez in March 2015[10] before facing Hee Jung Yuh for the vacant WBO female bantamweight title.
[13] In her next fight she faced Isabel Millan, making her second attempt for the WBA female flyweight title which was left vacant by Kentikian.