He enrolled at the Academy of Fine Arts of Bologna, and studied under Giovanni Battista Frulli.
[1] Angiolini won additional academic awards in 1817, for a painting representing St John the Baptist; and in 1821, for a figure drawing.
In 1824 he was awarded a four-year stipend to study in Rome, where he painted St Paul Apostle (1827), Ulysses in the House of the Shepherd Eumeo, and Socrates in Jail.
He completed the painting of the ceiling of San Sigismondo (1870) depicting the Blessed Imelda Lambertini and St Luigi Gonzaga.
His masterpiece, the curtain (sipario) of the Teatro Comunale, was destroyed in 1931 by fire; only sketches and studies remain.