Regular sweeps are conducted on marine vessels and on passengers at airports as part of security checks.During these inspections, if any suspected narcotic products are found, they are confiscated by the board and tested to determine their substance.

One such burning was done in June 2010 when the board destroyed 167 kilograms of seized cocaine at the Teshie Shooting Range in Accra.

[2] In 2009, NACOB announced a one-year campaign "to raise public awareness of the harmful effects of illicit drugs on the economic, social, political and cultural aspects of the country and its security.

One such collaboration led to the formation of the Operation West Bridge project in 2007, which was introduced at Ghana's Kotoka International Airport by the UK government.

[6] Problems that faces the board include the lack of adequate resources as well as remuneration for law enforcement personnel.