The show stars Don Johnson[1] and Cheech Marin as two Inspectors with the San Francisco Police Department's Special Investigations Unit (SIU).

The show begins with Bridges in his 40s, twice-divorced, and co-parenting his teenage daughter, Cassidy (Jodi Lyn O'Keefe).

Nash convinces recently retired Inspector Joe Dominguez (Cheech Marin), to return to the force and partner with him.

Bobby Bridges was reported as MIA, but turns up in the season 3 episode "Revelations", played by Jan-Michael Vincent.

Nash's father, Nick (James Gammon), suffers from mild dementia and has a habit of getting kicked out of nursing homes.

He eventually moves in with Nash, and is often involved in comic subplots that are intertwined with some of the show's dark humor themes.

Aiding Nash in his police work is the technically savvy Harvey Leek (Jeff Perry), a middle-aged "Deadhead" (a die hard Grateful Dead fan).

For the first sixteen episodes, the commander of the SIU was Lieutenant A. J. Shimamura (Cary-Hiroyuki Tagawa), a character who was said to have returned to his native Hawaii after failing to be promoted to captain.

[6] The show was produced by the Don Johnson Company and Carlton Cuse Productions in association with Rysher Entertainment for the first 4 seasons.

Season 6 changed the theme again, using another primarily instrumental piece with a bit of a techno beat to it, this time written by Velton Ray Bunch.

[4] Following its Friday night ratings battle (which it was losing to NBC's Law & Order: Special Victims Unit), the show was canceled.

The show would reportedly have series star Don Johnson reprising the titular role and serving as one of the showrunners for the project.

This revival would follow Nash, still running the SFPD's SIU and working to adjust to a new boss and to the changes of San Francisco in the 2020s.