She is best known for playing action heroes including Jasmine "Jaz" Khan in The Brave and Marjan Marwani in 9-1-1: Lone Star.
Karam was born in Jeddah, where her family was stationed, to a Northern Irish mother and a Lebanese-French father.
Her family moved around while Karam was growing up;[1] places she lived included Ireland,[2] Saudi Arabia, Jordan, Bahrain, and Dubai.
[5] She landed her first major role later that year, when she was cast as Sergeant Jasmine "Jaz" Khan on the military action drama series The Brave,[6] which ran for one season consisting of 13 episodes on NBC.
From 2020 to 2025, she was part of the main cast of the procedural drama series 9-1-1: Lone Star on Fox, playing the role of firefighter Marjan Marwani.