Natalia Giraldo Alzate (born 19 May 2003) is a Colombian professional footballer who plays as a goalkeeper for América de Cali and the Colombia women's national team.

Giraldo has played matches for the U20 and senior team.

[1] Giraldo made her debut with the Colombian senior team on 9 November 2019 against Argentina in a friendly match.

[2] On 3 July 2022, she was called up by Nelson Abadía to represent Colombia at the 2022 Copa América Femenina.

[3] On 4 July 2023, she was added to Colombia's 2023 FIFA Women's World Cup squad.