Natalie Osborne is a fictional character from the British soap opera Hollyoaks, played by Tiffany Mulheron.

Mulheron originally auditioned for the role of Roxy, a guest character, who was later murdered by serial killer Toby Mills (Henry Luxemburg).

Tina Baker from revealed that Natalie was being introduced as the niece of established character Jack Osborne (Jimmy McKenna).

[2] Natalie had several love interests during her time in the show, and Mulheron thought her character was "quite tarty".

[3] Natalie decides she wants a romantic relationship with her cousin, Darren Osborne (Ashley Taylor Dawson).

[4] Albert told an Inside Soap reporter that Debbie believed she had ruined her chances of reconciling with Darren after she got back with her ex-boyfriend Dan Hunter (Andy McNair).

[4] Mulheron decided to leave at the end of her contract in October 2004, so she could pursue different film and television roles.

At the 2004 British Soap Awards, Mulheron was nominated in the category of Sexiest Female for her portrayal of Natalie.

The sexy madam charmed the pants off many a man during her brief stay but she was unceremoniously sent back to Scotland after getting pregnant.