[1] She previously served as in State Duma between 2001 and 2010, where for six years she headed the powerful Natural Resources Committee.

Natalya Komarova is a graduate of the Kommunarsk Mining-Metallurgical Institute (now Donbas State Technical University).

On 8 February 2010, Komarova's credentials were endorsed by the State Duma and Russian President Dmitry Medvedev to be appointed Governor of Khanty-Mansia, shortly after which she took office.

She successfully ran for the position in 2015 after Russia re-adopted gubernatorial elections, a system that was previously abandoned ten years prior.

The same day, President Vladimir Putin appointed mayor of Tyumen Ruslan Kukharuk acting Governor.