[3] Her breakthrough came in 2018 when she won bronze as part of the Russian relay team.

In the 2018–19 season, Nepryayeva became the first Russian female skier to finish in the top 3 of the Tour de Ski.

[4] At the 2019 FIS Nordic World Ski Championships, Nepryayeva became the first female Russian skier since 2007 to medal in skiathlon (then known as double pursuit).

Nepryayeva became the first Russian female skier to win the Tour de Ski, doing so during the 2021–22 World Cup season.

[6] Furthermore, she won the World Cup, despite being excluded from the last two stages due to sanctions related to the Russian invasion of Ukraine.