Her winning single, "In punta di piedi", was released immediately after the final of the show, and debuted atop the FIMI Top Digital Downloads chart.

In 2011, Nathalie competed in the Big Artists section of the 61st Sanremo Music Festival, placing 7th in a field of 14 with the song "Vivo sospesa", which was released as the lead single from her debut album with the same title.

At a press conference presenting the fourth series of X Factor, Rai 2 director Massimo Liofredi announced that the winner of the competition "might" advance to represent Italy in the Eurovision Song Contest 2011, rather than participate in the Sanremo Music Festival, like in previous years.

The song finished 7th in a field of 14 and was released as the lead single from Nathalie's debut studio album, titled Vivo sospesa and issued by Sony Music in February 2011.

[8] The single preceded her second studio album, Anima di vento, released on 17 September 2013 and also featuring duets with Franco Battiato and Toni Childs.