Delfouneso had a series of loan moves to Football League Championship sides while at Aston Villa, followed by permanent spells at Blackpool, Blackburn Rovers and Swindon Town.

Delfouneso made his competitive first-team début as a substitute in the away leg of the UEFA Cup second round match against Icelandic team FH Hafnarfjörður.

He made his first competitive start in a UEFA Cup tie against MŠK Žilina, scoring with a left-footed volley after just half an hour.

[5] Delfouneso made his first domestic senior appearance on 4 January 2009, in an FA Cup tie against Gillingham at Priestfield Stadium, which Villa won 2–1.

On 16 February, it was reported that Crystal Palace manager Neil Warnock was interested in taking Delfouneso to Selhurst Park on loan.

On 6 November 2009, Delfouneso signed a new two-and-a-half-year contract with Aston Villa, keeping him at the club until the end of the 2011–12 season.

In January 2010, O'Neill said that Delfouneso, along with fellow youngsters Marc Albrighton and Ciaran Clark, were the subject of many loan offers from various other clubs.

However, he went on to emphasise his confidence that the trio were good enough to remain as vital squad members on the fringes of Aston Villa's first team.

On 6 November 2010, Delfouneso started his first Premier League game against Fulham due to Emile Heskey, John Carew and Agbonlahor being injured.

On 20 May 2014, Aston Villa announced via their Twitter page that Delfouneso, along with Marc Albrighton, had been released from his contract and would be a free agent for the start of the 2014–15 season.

Delfouneso scored past on-loan Aston Villa teammate Brad Guzan just five minutes into his first start for The Clarets.

[17] After two previous loan spells at Bloomfield Road, Delfouneso signed a one-year contract with Blackpool, with the option of a second, in July 2014.

[20] On 6 August 2015, following Delfouneso's release from Blackpool, he signed for Blackburn Rovers on a one-year deal and was handed the number 7 shirt.

On 11 August 2015, he scored his first Rovers goal with a header against Shrewsbury Town in a 2–1 defeat at Ewood Park in the Football League Cup first round.

[27] After scoring four goals in pre-season[28][29][30] his competitive debut came on 5 September in Bolton's first match of the season, a 1–2 home defeat against Bradford in the first round of the EFL Cup.