[3] In 1850, living with them were Paschal family members Eugenia, age 16; Ada, 14; Cara, 12; Mary, 9; Henry G., 6; George M., 3; and Lizzie C., a baby.

[6][7] Nathaniel Paschall was apprenticed as a "bound boy" early in 1814, when he was not quite twelve, to Joseph Charless of the Missouri Gazette to learn the trade of printing.

When his apprenticeship expired in 1823, he continued to work with Edward Charless, the son of the paper's founder and its new owner.

[10] In 1860, Paschall, as editor of The Republican, successfully placed strong pressure on Claiborne Jackson and Thomas C. Reynolds to declare their support for Stephen Douglas's candidacy for the Presidency of the United States.

Courthouse with jurist Hamilton R. Gamble, banker James E. Yeatman, fur trader Frank Blair, and businessman Robert Campbell, with others, to urge the federal government to refrain from coercion against the states that had already taken steps to secede from the United States.

[11] Of Paschall, veteran St. Louis newspaperman William Hyde (who succeeded him as editor), recalled in 1896:[12] Mr. Paschall had had only what may be styled a newspaper education and equipment, graduating from the printer's case and imbibing the great fund of information contained in what went upon his galleys or columns of type.But he was a thinker.