Nathaniel Seymour Thomas (June 30, 1867 - April 1, 1937) was second bishop of the Episcopal Diocese of Wyoming, serving from 1909 to 1927.

He was educated in Minneapolis, and Saint Paul, before studying at the University of Minnesota and graduating with a Bachelor of Arts in 1890.

He also became professor of Pastoral Care at the Philadelphia Divinity School, while in 1894, he became rector of St Paul's Church in Leavenworth, Kansas.

On February 27, 1909, Thomas was elected Missionary Bishop of Wyoming, a post which he accepted.

He resigned on June 1, 1927, and became chairman of the board of oversees at the Philadelphia Divinity School.