In May 2011, National leased a Boeing 757-200 in an all-passenger configuration and began operating the aircraft in an on-demand charter basis from Dubai.

Originally based at Willow Run Airport in Ypsilanti, Michigan, the company moved in 2012 to Orlando, Florida.

In September, 2015, National announced scheduled passenger service from its hub at Orlando Sanford International Airport using their two active 757s.

[6][7][8] In March 2016, National was slated to start 757 service from Long Island MacArthur Airport in Ronkonkoma, NY to Puerto Rico.

According to Garrett Matyas, the company's human resources director, the company originally considered Ann Arbor, Michigan, and was in talks with the Michigan Economic Development Corp.[12] Instead, Matyas said that the airline moved to Florida due to an environment friendly towards business interests.

The New Zealand Defence Force (NZDF) indefinitely postponed using National Airlines for its airlift requirements after Flight 102 crashed.

Although Taliban spokesmen claimed responsibility for the destruction of the aircraft, initial reports based on communications from the crew after takeoff indicated that the crash probably resulted from a load shift, causing the aircraft to experience a high-aft center of gravity, becoming unstable and eventually leading to the loss of control by the pilots.

On Sep 14th 2015 the NTSB released their final report, concluding the probable cause of the crash thus: "National Airlines' inadequate procedures for restraining special cargo loads, which resulted in the loadmaster's improper restraint of the cargo, which moved aft and damaged hydraulic systems Nos.

[23] On May 1, 2022, flight NCR761, a National Airlines Airbus A330-200 (registration N819CA) struck a light pole in St. Kitts' Robert L. Bradshaw Int'l Airport.

During taxi, the aircraft's left wing clipped one of the airport's tall light pole, causing it to nearly fall over.