National Brain Research Centre

Scientists and students at NBRC come from diverse academic backgrounds, including biological, computational, mathematical, physical, engineering, and medical sciences.

The creation was subsequently declared on 14 November 1997 as a part of the Golden Jubilee celebrations of India's Independence and the birth date of the former Prime Minister, Jawaharlal Nehru.

Monitoring glutathione (GSH), an antioxidant molecule in the brain, aids in the early identification of AD and mapping out therapeutic invention.

Presently, they are investigating the role of two GSH conformations and link between iron deposition and oxidative stress (OS) in the hippocampal formation in AD.

This first global study analyzed structural, spectroscopic, and behavioral changes in the brains of recovered/asymptomatic patients using a novel non-invasive MRS neuroimaging technique.

Findings suggest that glutamate and GABA levels are potential parameters to monitor mental health and psychiatric disease-associated conditions.

[22] Scientists studied the specific role of the human thalamus as causal outflow hub in reorganizing directed information flow and connectivity among large-scale major neurocognitive networks during brain aging.

This reorganization of directed functional connectivity with age during spontaneous activity highlights the importance of subcortical areas even during stimulus independent processing.

[25] This work on focused on the regeneration of nervous system, wherein lost neuronal function was found to be restored after injury in roundworm model.

The findings established that the axon fusion process has functional significance in the maintenance of neuronal integrity throughout the life span of an organism.

HMGB1 is crucial for regulating susceptibility to SARS-CoV-2, whereas S-receptor binding body (RBD) and Orf3a proteins are required for maximal SARS-CoV replication and virulence.

Benefits of anti-inflammatory properties in glycyrrhizin are: 1) Lowering the severity of the disease, 2) Mitigating viral replication by as much as 90%, and 3) Fighting the "storm of cytokines".