It starts at Nakrekal of Telangana and ends at Yerpedu of Andhra Pradesh.

[1][2] New Alignment of this National Highway 565, was Opened to traffic between Chunchuluru to Rapur through Penchelakona Forest.

It starts at junction of National Highway 65 Nakrekal and passes through Nalgonda on the Nagarjuna Sagar road until Telangana border and then through Macherla, Yerragondapalem, Markapur, Chinarikatla junction (PODILI), Kanigiri, Pamur, Duttalur, Penchalakona, Rapur, and Venkatagiri before terminating at National Highway 71 at Yerpedu in Andhra Pradesh.

[3][4] State–wise route length (in km): NHAI has taken up widening of this highway into two lane with paved shoulders throughout the stretch.

Widening works were expected to be completed by the end of 2017.