NH-53 traverses the states of Gujarat, Maharashtra, Chhattisgarh and Odisha in India.

[2] The road is the part of AH46 network in India and it is officially listed as running over 1975 km (1227 mi) from Kolkata to Surat.

[3] The National Highway Authority of India (NHAI) has created a Guinness World Record of constructing the longest highway stretch of 75 kilometres (km) between Amravati and Akola in the least time—105 hours and 33 minutes.

Route of primary national highway 53 passes through four states of India.

Chhattisgarh border - Bargarh, Sambalpur, Tileibani, Deogarh, Barkote, Pallahara, Samal Barrage, Godibhanga, Talcher, Kamakhyanagar, Bhuban, Sukinda, Dubri, Chandhikhol, Haridaspur, Silipur, Bhutamundai, Paradip Port.