Among the artists represented are António Silva Porto, António Carneiro, António Soares dos Reis, Miguel Ângelo Lupi, Columbano Bordalo Pinheiro, Amadeo de Souza Cardoso, Abel Manta, Dórdio Gomes, Adriano Sousa Lopes, José de Almada Negreiros, Nadir Afonso, Mário Eloy, Francisco Augusto Metrass, Mónica de Miranda, Auguste Rodin, and many others.

Since 1911, the Chiado Museum has occupied part of the old Convent of São Francisco (Saint Francis) in Lisbon, a building of mediaeval origin.

[13][14] 2022 As the museum is a space for dialogue and that caters for all age groups, the exhibition for children "The other life of animals" was organised.

[15] MNAC also organized the first ever exhibition of Veloso Salgado in France, with about 60 artworks, making known the connection of this master to the painters of Wissant.

[16] It also inaugurated Nelson Ferreira's exhibition "Painting rarefied the spirit" which was the fruit of the first artistic residency in MNAC's Sculpture Garden.