The Memorial in Commemoration of Famines' Victims in Ukraine was erected on the slopes of the Dnipro river in 2008, welcoming its first visitors on 22 November 2008.

[5] On 31 July 2015, the Ministry of Culture of Ukraine renamed the museum in order to reflect the singular instance of the famine-genocide known as Holodomor.

The plural has been removed in order to offset the understanding of the Holodomor being the 1932–1933 famine as being exclusively deemed to be genocidal in nature.

[2][6] On July 12, 2023, according to the official web portal of the Ukrainian Parliament, the Verkhovna Rada of Ukraine plans to allocate additional funds to complete the construction and commissioning of the National Museum of the Holodomor Genocide.

The allocation of funds will make it possible to complete the entire complex of construction work at the museum in a short time.

The memorial complex was conceptualized and designed by the Ukrainian folk artist Anatoliy Haydamaka and architect Yuriy Kovalyov.

Picking up wheat left on the collective farm fields after reaping was considered a crime and was punishable by up to 10 years of imprisonment or even death.

Visitors also have an opportunity to browse the volumes of the National Memory Book of Famine's Victims of 1932–1933 and provide information about their relatives who died of starvation in Ukraine.

The symbolic black boards document the names of Ukrainian towns and villages which had suffered during the dark years of the famines.

General admission fee to the underground section of the museum (the Hall of Memory) is ₴30 for adults, ₴20 for Students, ₴15 for children.

It plans to expand its educational efforts to include outreach programs for schools, post-secondary establishments and public libraries, as well as to offer teachers training sessions and seminars on the history of the Holodomor.

The museum aims to expand its activities to become a global centre for research on famine, victimization and human rights.