The Colombian National Symphony Orchestra is part of the 'National Association of Symphonic Music' (Asociación Nacional de Música Sinfónica), a non-profit organization that receives extensive support from the Colombian government to maintain the orchestra and to provide financial support to the other professional symphony orchestras in the country.
From 2003 to 2007, the orchestra's artistic direction was under the management of three music directors: Luis Biava (conductor-in-residence of the Philadelphia Orchestra until 2004), Alejandro Posada (then-music director of the Symphonic Orchestra of Castile and León (Orquesta Sinfónica de Castilla y León)), and Eduardo Carrizosa (then the assistant conductor of the Bogota Philharmonic (Orquesta Filarmónica de Bogotá)).
In 2007, the orchestra opened a search process for a single principal conductor and artistic director.
This search led to the appointment of Baldur Brönnimann as principal conductor and artistic director, who held the post from 2008 to 2012.
In 2016, Olivier Grangean became principal conductor and artistic director of the orchestra.