Nazareth Newton was the youngest daughter of Sir John Newton (d. 1568) of East Harptree, Somerset, and Barrs Court, Gloucestershire, and Margaret, daughter of Sir Anthony Poyntz of Iron Acton and Elizabeth Huddesfield.
At Harptree, the Newton family lived at Eastwood, a house built from the demolished stone of Richmont Castle.
[1] Her sister Frances Newton, who married William Brooke, 10th Baron Cobham, was a lady of the bedchamber.
Nazareth Newton was the third wife of Sir Thomas Southwell (d. 1568) of Woodrising, Norfolk.
In March 1571, Nazareth Southwell was given a gift of properties confiscated from John Eliot, a London merchant.