When Promedon of Naxos, a very good friend of Hypsicreon, visited him in Miletus, Neaera fell in love with the guest.
She could not show her feelings in her husband's presence, but after some time Promedon came to Miletus again while Hypsicreon happened to be away, whereat she decided to take a chance.
Neara then ordered for the doors of the room to be locked and persisted in her advances, eventually forcing him to satisfy her desires.
When Hypsicreon arrived at Naxos in search for her, she took up a suppliant's position at the sacred hearth in Prytaneum.
The Milesians declared a war on Naxos over the incident and could have won if not for the stratagem of Polycrite.