He clerked for Judge Barrington D. Parker for two years, then worked in a Washington, DC law firm from 1974 to 1979, before joining the United States Department of Justice.
As director, he led AIPAC's support of the Oslo Accords, sparring with rival lobbyists Zionist Organization of America over the issue.
[8] He apparently clashed with the board of directors, however, and resigned shortly after Benjamin Netanyahu's surprise victory in the 1996 Israel prime ministerial election to return to work on Holocaust-related issues.
[8][9] In the documentary I have Never Forgotten You about famed Nazi hunter Simon Wiesenthal, Sher is shown criticizing Wiesenthal, saying, "There were and still remain today alive, many people who personally suffered at the hands of Joseph Mengele and to hold out hope to them, and these people held out hope, that their tormenter, their torturer, this mass murderer would be brought to justice, when the information was not accurate, I think is cruel."
[3] Sher was in the news for his representation of his friend Morris Talansky, who is a witness in the investigation of Israeli Prime Minister Ehud Olmert.