It was recognised as a breed by the Ente Nazionale della Cinofilia Italiana in 1949,[1] and accepted by the Fédération Cynologique Internationale in 1956.

[2] It descends from the traditional guard dogs of central Italy,[3] and is closely related to the Cane Corso.

The Neapolitan Mastiff derives from the traditional catch and guard dogs of central Italy.

[3][1] He drew up the first standard, which in 1949 was officially recognised by the Ente Nazionale della Cinofilia Italiana.

The preferred coat colours are black, grey and leaden, but mahogany, fawn, fulvous, hazelnut, dove-grey and isabelline are also acceptable; all coats may be brindled, and minor white markings on the toes and chest are tolerated.