Necitumumab (INN) is a recombinant human IgG1 monoclonal antibody used as an antineoplastic, which is manufactured by Eli Lilly.
It binds to the epidermal growth factor receptor (EGFR).
[4] The US FDA approved necitumumab under the brand name Portrazza for use with gemcitabine and cisplatin in previously untreated metastatic squamous non-small-cell lung carcinoma (NSCLC).
[5][6][3] It was counterproductive in non-squamous non-small-cell lung carcinoma.
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