3R0N, 4DFH, 4DFI, 4HZA581919294ENSG00000130202ENSMUSG00000062300Q92692P32507NM_001042724NM_002856NM_001159724NM_008990NP_001036189NP_002847NP_001153196NP_033016Poliovirus receptor-related 2 (PVRL2), also known as nectin-2 and CD112 (formerly herpesvirus entry mediator B, HVEB), is a human plasma membrane glycoprotein.

This protein is one of the plasma membrane components of adherens junctions.

Variations in this gene have been associated with differences in the severity of multiple sclerosis.

Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

[5] This article incorporates text from the United States National Library of Medicine, which is in the public domain.