NPO 2 tends to broadcast arts, culture, politics, news, current affairs, documentaries and religious programmes.

The channel is also available on cable companies in its overseas dependencies in the Caribbean, either live or time-shifted.

The reason for this change is to make the channels and their programmes more recognizable.

[7] NPO 2 is aimed at viewers who wish for a more intelligent style of programming.

Fixtures of the channel's schedule include: Cultural programmes are generally broadcast during the day on Saturdays, and Sunday mornings are home to religious programmes, such as the BBC's Songs of Praise.