The museum is home to the original Gemini 8 spacecraft piloted by Armstrong to perform the world's first space docking, two of Armstrong's space suits, multiple items from the Apollo Program missions, a Moon rock brought back during the Apollo 11 mission, and an F5D Skylancer.

The National Aviation Heritage Area (NAHA) lists the Armstrong Air & Space Museum as one of its partner organizations, citing its preservation of historically relevant material related to the history of aerospace.

Local efforts to raise the necessary money began immediately after the announcement, with a number of Wapakoneta residents forming a centralized fundraising committee.

The design was a geometric, steel-reinforced concrete building with large earth mounds surrounding the structure to resemble being underground.

Years later, Crouch was named as a Curator for the National Air and Space Museum in Washington DC.

Many of the museum's inaugural artifacts included the Gemini VIII spacecraft, an H-1 rocket engine, and Armstrong's spacesuits.

[4] Another major expansion occurred in 2019, which included adding the Neil Armstrong STEM Inspiration Center, a classroom space that allows schools groups to conduct hands-on programming and experiments.

[5] In August 2020, the first production Learjet 28, which was used by Neil Armstrong to set five aerospace records, was donated to the museum.