[9] Following his internship and residency, Bressler joined the faculty at Harvard Medical School as an instructor of ophthalmology and the Massachusetts Eye and Ear Infirmary.
[13] As a result of his academic accomplishments, Bressler was the inaugural recipient of the James P. Gills Professor of Ophthalmology at Johns Hopkins in 2000.
[1] Alongside his wife, Bressler was the co-recipient of the 2008 Gertrude D. Pyron Award from the American Society of Retina Specialists for "outstanding vision scientists whose work contributes to knowledge about vitreoretinal disease.
[15] In 2017, Bressler co-published a study that demonstrated the ability of a form of AI known as deep learning to accurately detect age-related macular degeneration.
Following the study, Bressler and his team evaluated algorithms and comparing methods before ultimately determining that low-shot deep learning does have the potential to overcome limitations imposed by a low number of training images in retinal diagnostics.