[1] He moved to Toronto Canada around 1830, where he worked as an agent for his brother Ransom and took up painting.
[2] Cook was a self-taught artist and over 170 of his portraits have been found, including many prominent people from Canada, Saratoga Springs, Rochester, Buffalo, Rome, Utica and elsewhere.
His work is in museums and private collections mostly in the Northeastern US and Ontario, Canada.
Nelson Cook was married to Esther Freeman and had one daughter, Marion, born in Canada.
He died in Saratoga Springs in 1892 and is believed to be buried in Greenridge Cemetery.